The future of transcatheter mitral valve interventions: competitive or complementary role of repair vs. replacement?

نویسندگان

  • Francesco Maisano
  • Ottavio Alfieri
  • Shmuel Banai
  • Maurice Buchbinder
  • Antonio Colombo
  • Volkmar Falk
  • Ted Feldman
  • Olaf Franzen
  • Howard Herrmann
  • Saibal Kar
  • Karl-Heinz Kuck
  • Georg Lutter
  • Michael Mack
  • Georg Nickenig
  • Nicolo Piazza
  • Mark Reisman
  • Carlos E Ruiz
  • Joachim Schofer
  • Lars Søndergaard
  • Gregg W Stone
  • Maurizio Taramasso
  • Martyn Thomas
  • Alec Vahanian
  • John Webb
  • Stephan Windecker
  • Martin B Leon
چکیده

Transcatheter mitral interventions has been developed to address an unmet clinical need and may be an alternative therapeutic option to surgery with the intent to provide symptomatic and prognostic benefit. Beyond MitraClip therapy, alternative repair technologies are being developed to expand the transcatheter intervention armamentarium. Recently, the feasibility of transcatheter mitral valve implantation in native non-calcified valves has been reported in very high-risk patients. Acknowledging the lack of scientific evidence to date, it is difficult to predict what the ultimate future role of transcatheter mitral valve interventions will be. The purpose of the present report is to review the current state-of-the-art of mitral valve intervention, and to identify the potential future scenarios, which might benefit most from the transcatheter repair and replacement devices under development.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Mitral valve disease, atrial fibrillation, and device therapy.

Transcatheter mitral interventions have been developed to address an unmet need, and as alternatives to surgery in patients at high risk or considered inoperable. Beyond MitraClip therapy, alternative repair technologies are being developed to expand the armamentarium of transcatheter intervention. Recently, the feasibility of transcatheter mitral valve implantation in native non-calcified valv...

متن کامل

High-risk Coronary Artery Bypass Grafting and Mitral Valve Replacement in a HIV Positive Patient

Certain subsets of high-risk mitral valve patients are not suitable candidates for transcatheter therapies. The objective of this report is to present a young patient with combined mitral valve and coronary artery disease to illustrate these challenges.In this report, we present a 47-year-old man with longstanding HIV infection who was referred with severe mitral regurgitation (MR) and profound...

متن کامل

Mitral Valve Replacement—Current and Future Perspectives

The favorable outcomes achieved with modern mitral valve repair techniques redefined the role of mitral valve replacement. Various international databases report a significant decrease in replacement procedures performed compared with repairs, and contemporary guidelines limit the application of surgical mitral valve replacement to pathology in which durable repair is unlikely to be achieved. T...

متن کامل

Right sided heart evaluation after successful mitral valve replacement.

Introduction: It is well-documented that right-sided heart dysfunction and significant tricuspid valve regurgitation (TVR) have adverse effects on patient outcomes after left-sided heart valve surgery. Therefore, the evaluation of right ventriclular (RV) function and TR severity in patients who had undergone mitral valve replacement (MVR), associated with/without concomitant su...

متن کامل

Catheter-based or surgical repair of the highest risk secondary mitral regurgitation patients.

Surgical mitral valve repair (MVR) remains the standard of care for patients with severe valve incompetence with clear, proven benefit for patients with primary mitral regurgitation (MR). Secondary MR is a primary disease of the left ventricular (LV) myocardium. Up to 50% of patients develop secondary MR after an acute myocardial infarction (ischemic MR), with approximately 10% of these having ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • European heart journal

دوره 36 26  شماره 

صفحات  -

تاریخ انتشار 2015